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CD2AP Antibody

CAT: 0223-23-184Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-184Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
NCBI Gene ID
23607
Swiss Prot
Q9Y5K6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human CD2AP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 90kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
Cd2ap
Positive Control 2
Raji
Positive Control 3
MCF7
Positive Control 4
SW480
Positive Control 5
HL-60
Positive Control 6
Mouse kidney
NCBI Official Name
CD2 associated protein
NCBI Organism
Homo sapiens
Other Product Names
CMS, CD2-associated protein, Cas ligand with multiple Src homology 3 (SH3) domains, adapter protein CMS, cas ligand with multiple SH3 domains
Tested Applications
WB
Physical Properties
Liquid

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