CFHR3 Antibody

• Background:

  The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  10878

• Swiss Prot:

  Q02985

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 45kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CFHR3

• Positive Control 2:

  HepG2

• Positive Control 3:

  NIH/3T3

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  Complement factor H related 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CFHL3, DOWN16, FHR-3, FHR3, HLF4, complement factor H-related protein 3, H factor-like 4, H factor-like protein 3

• Tested Applications:

  WB

• Physical Properties:

  Liquid