ADAM15 Antibody

• Background:

  The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

• NCBI Gene ID:

  8751

• Swiss Prot:

  Q13444

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human ADAM15

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse heart

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 93kDa

• Fragment:

  IgG

• Symbol:

  ADAM15

• Positive Control 2:

  Mouse kidney

• Positive Control 3:

  Mouse brain

• NCBI Official Name:

  ADAM metallopeptidase domain 15

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ADAM15, MDC15

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid