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PLCG1 Antibody

CAT: 0223-23-121Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-121Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5335
Swiss Prot
P19174
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PLCG1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 160kDa
Fragment
IgG
Symbol
PLCG1
Positive Control 2
Jurkat
Positive Control 3
HepG2
Positive Control 4
Mouse brain
Positive Control 5
Mouse lung
Positive Control 6
Rat brain
NCBI Official Name
Phospholipase C, gamma 1
NCBI Organism
Homo sapiens
Other Product Names
PLCG1, Phospholipase C, gamma 1, Phospholipase C-148, Phosphoinositidase C, Phospholipase C-II, Inositoltrisphosphohydrolase, PLC-gamma-1, PLC1, PLC-148, PLC-II, PLC148, NCKAP3, Phospholipase C-gamma-1, PLCgamma1
Tested Applications
WB, IHC
Physical Properties
Liquid

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