PLCD1 Antibody

• Background :

  Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]) .

• NCBI Gene ID :

  5333

• Swiss Prot :

  P51178

• Accession Number :

  P51178

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PLCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PLCD1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  86 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PLCD1

• NCBI Official Name :

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

• Background Reference 03 :

  Guo, Y., et al. J. Biol. Chem. 285 (32) :24999-25008 (2010)

• Background Reference 04 :

  Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010)

• Other Product Names :

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1, PLCD1

• Tested Applications :

  WB

• Protein ID :

  206729887

• Physical Properties :

  Liquid