PLCD1 Antibody

CAT: 0223-56-760Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-760Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]) .
NCBI Gene ID
5333
Swiss Prot
P51178
Accession Number
P51178
Host
Rabbit
Reactivity
Human
Immunogen
This PLCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PLCD1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PLCD1
NCBI Official Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)
Background Reference 03
Guo, Y., et al. J. Biol. Chem. 285 (32) :24999-25008 (2010)
Background Reference 04
Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010)
Other Product Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1, PLCD1
Tested Applications
WB
Protein ID
206729887
Physical Properties
Liquid

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