PLCD1 Antibody

• Background:

  Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]) .

• NCBI Gene ID:

  5333

• Swiss Prot:

  P51178

• Accession Number:

  P51178

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PLCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PLCD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PLCD1

• NCBI Official Name:

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

• Background Reference 03:

  Guo, Y., et al. J. Biol. Chem. 285 (32) :24999-25008 (2010)

• Background Reference 04:

  Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010)

• Other Product Names:

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1, PLCD1

• Tested Applications:

  WB

• Protein ID:

  206729887

• Physical Properties:

  Liquid