ITGA2 Antibody, KO Validated

CAT: 0223-23-063Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-23-063Size:100 µL
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Background
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
3673
Swiss Prot
P17301
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ITGA2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 150kDa
Fragment
IgG
Symbol
ITGA2
Positive Control 2
HT-1080
NCBI Official Name
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
NCBI Organism
Homo sapiens
Other Product Names
ITGA2, Alpha2 integrin, BR, CD49b antigen, CD49B, Integrin alpha2, Integrin Alpha 2, Integrin alpha-2, HPA-5, VLA-2, VLAA2, VLA-2 subunit alpha, Collagen receptor, GPIa, Platelet antigen Br, Platelet glycoprotein GPIa, VLA2 receptor, alpha-2 subunit
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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