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UBA3 Antibody

CAT: 0223-22-991Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-991Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
9039
Swiss Prot
Q8TBC4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 234-463 of human UBA3 (NP_003959.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa/104kDa
Fragment
IgG
Symbol
UBA3
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
Jurkat
Positive Control 5
HL-60
Positive Control 6
Mouse brain
NCBI Official Name
Ubiquitin-like modifier activating enzyme 3
NCBI Organism
Homo sapiens
Other Product Names
UBA3, DKFZp566J164, MGC22384, UBE1C, hUBA3, NAE2
Tested Applications
WB, IHC
Physical Properties
Liquid

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