SYNCRIP Antibody

• Background:

  This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.

• NCBI Gene ID:

  10492

• Swiss Prot:

  O60506

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SYNCRIP (NP_001153146.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50-100kDa

• Fragment:

  IgG

• Symbol:

  SYNCRIP

• Positive Control 2:

  Jurkat

• Positive Control 3:

  A-431

• Positive Control 4:

  MCF7

• Positive Control 5:

  BT-474

• Positive Control 6:

  Mouse heart

• NCBI Official Name:

  Synaptotagmin binding, cytoplasmic RNA interacting protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SYNCRIP, PP68, NSAP1, GRYRBP, HNRNPQ, HNRPQ1, GRY-RBP, hnRNP-Q

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid