FASTK Antibody

• Background:

  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

• NCBI Gene ID:

  10922

• Swiss Prot:

  Q14296

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 360-549 of human FASTK (NP_006703.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  NCI-H460

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 61kDa

• Fragment:

  IgG

• Symbol:

  FASTK

• Positive Control 2:

  Mouse brain

• NCBI Official Name:

  Fas-activated serine/threonine kinase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Fas-activated serine/threonine kinase, FAST kinase, FASTK

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid