FASTK Antibody

• Background :

  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

• NCBI Gene ID :

  10922

• Swiss Prot :

  Q14296

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 360-549 of human FASTK (NP_006703.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  NCI-H460

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 61kDa

• Fragment :

  IgG

• Symbol :

  FASTK

• Positive Control 2 :

  Mouse brain

• NCBI Official Name :

  Fas-activated serine/threonine kinase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Fas-activated serine/threonine kinase, FAST kinase, FASTK

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid