HIRIP3 Antibody

• Background:

  The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• NCBI Gene ID:

  8479

• Swiss Prot:

  Q9BW71

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 417-556 of human HIRIP3 (NP_003600.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 62kDa

• Fragment:

  IgG

• Symbol:

  HIRIP3

• Positive Control 2:

  HeLa

• Positive Control 3:

  U-937

• Positive Control 4:

  Jurkat

• Positive Control 5:

  Mouse skeletal muscle

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  HIRA-interacting protein 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HIRA-interacting protein 3, HIRIP3

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid