CTNS Antibody

• Background:

  This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  1497

• Swiss Prot:

  O60931

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CTNS (NP_001026851.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 42kDa

• Fragment:

  IgG

• Symbol:

  CTNS

• Positive Control 2:

  SW480

• Positive Control 3:

  HepG2

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Mouse skeletal muscle

• NCBI Official Name:

  Cystinosin, lysosomal cystine transporter

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CTNS, Cystinosin, Cystinosis, nephropathic, CTNS-LSB, PQLC4

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid