TSHR Antibody

• Background:

  The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  7253

• Swiss Prot:

  P16473

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Symbol:

  TSHR

• Positive Control 2:

  SKOV3

• Positive Control 3:

  OVCAR3

• Positive Control 4:

  Mouse ovary

• Positive Control 5:

  Mouse thymus

• Positive Control 6:

  Mouse eye

• NCBI Official Name:

  Thyroid stimulating hormone receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TSHR, LGR3, MGC75129, hTSHR-I, CHNG1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid