DNMT3A Antibody

• Background :

  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

• NCBI Gene ID :

  1788

• Swiss Prot :

  Q9Y6K1

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human DNMT3A (NP_715640.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  MCF7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 140kDa

• Fragment :

  IgG

• Symbol :

  DNMT3A

• Positive Control 2 :

  HT-29

• Positive Control 3 :

  BT-474

• Positive Control 4 :

  HepG2

• Positive Control 5 :

  SW620

• NCBI Official Name :

  DNA (cytosine-5) -methyltransferase 3A

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  DNA (cytosine-5) -methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid