PPOX Antibody

• Background :

  This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

• NCBI Gene ID :

  5498

• Swiss Prot :

  P50336

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPOX (NP_001116236.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 51kDa

• Fragment :

  IgG

• Symbol :

  PPOX

• Positive Control 2 :

  Mouse spleen

• Positive Control 3 :

  Mouse liver

• Positive Control 4 :

  Mouse kidney

• NCBI Official Name :

  Protoporphyrinogen oxidase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PPO, V290M, VP, protoporphyrinogen oxidase

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid