FMOD Antibody

• Background:

  Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  2331

• Swiss Prot:

  Q06828

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 19-376 of human FMOD (NP_002014.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 45kDa

• Fragment:

  IgG

• Symbol:

  FMOD

• Positive Control 2:

  Mouse spleen

• Positive Control 3:

  Rat spleen

• Positive Control 4:

  Rat skeletal muscle

• NCBI Official Name:

  Fibromodulin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FMOD, SLRR2E, FM

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid