RHOH Antibody

• Background:

  The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP) -metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.

• NCBI Gene ID:

  399

• Swiss Prot:

  Q15669

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human RHOH (NP_004301.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 27kDa

• Fragment:

  IgG

• Symbol:

  RHOH

• Positive Control 2:

  SW620

• Positive Control 3:

  Jurkat

• Positive Control 4:

  HT-29

• Positive Control 5:

  Mouse spleen

• Positive Control 6:

  Mouse thymus

• NCBI Official Name:

  Rho-related GTP-binding protein RhoH

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Rho-related GTP-binding protein RhoH, GTP-binding protein TTF, Translocation three four protein, RHOH, ARHH, TTF

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid