ITGA5 Antibody

CAT: 0223-22-054Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-054Size:100 µL
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Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
NCBI Gene ID
3678
Swiss Prot
P08648
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 750-1000 of human ITGA5 (NP_002196.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 135kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ITGA5
Positive Control 2
NIH/3T3
Positive Control 3
HT-1080
Positive Control 4
Rat heart
Positive Control 5
Mouse heart
NCBI Official Name
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
NCBI Organism
Homo sapiens
Other Product Names
ITGA5, FNRA, Integrin alpha-5, Integrin Alpha 5, Integrin alpha-F, VLA-5, CD49e, CD49e antigen, VLA5A
Tested Applications
WB
Physical Properties
Liquid

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