ITGAE Antibody

• Background :

  Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

• NCBI Gene ID :

  3682

• Swiss Prot :

  P38570

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Immunology, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 110kDa

• Fragment :

  IgG

• Symbol :

  ITGAE

• Positive Control 2 :

  SW620

• Positive Control 3 :

  HeLa

• Positive Control 4 :

  Mouse lung

• Positive Control 5 :

  Mouse thymus

• NCBI Official Name :

  Integrin alpha-E

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid