PVR Antibody

• Background:

  The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5817

• Swiss Prot:

  P15151

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human PVR (NP_006496.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  PVR

• NCBI Official Name:

  Poliovirus receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid