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PVR Antibody

CAT: 0223-19-835Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-19-835Size:100 µL
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Background
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5817
Swiss Prot
P15151
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human PVR (NP_006496.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
PVR
NCBI Official Name
Poliovirus receptor
NCBI Organism
Homo sapiens
Other Product Names
Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS
Tested Applications
WB, IF
Physical Properties
Liquid

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