PSCA Antibody

• Background:

  This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  8000

• Swiss Prot:

  O43653

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 12-114 of human PSCA (NP_005663.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  Mouse kidney

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 36kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PSCA

• Positive Control 2:

  Mouse heart

• Positive Control 3:

  Mouse testis

• Positive Control 4:

  Mouse eye

• NCBI Official Name:

  Prostate stem cell antigen

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PSCA, prostate stem cell antigen, PRO232

• Tested Applications:

  WB

• Physical Properties:

  Liquid