MERTK Antibody

• Background:

  This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

• NCBI Gene ID:

  10461

• Swiss Prot:

  Q12866

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 160kDa

• Fragment:

  IgG

• Symbol:

  MERTK

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse spleen

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  C-mer proto-oncogene tyrosine kinase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MERTK, c-mer proto-oncogene tyrosine kinase , MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid