MERTK Antibody

• Background :

  This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

• NCBI Gene ID :

  10461

• Swiss Prot :

  Q12866

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  22Rv1

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 160kDa

• Fragment :

  IgG

• Symbol :

  MERTK

• Positive Control 2 :

  Mouse liver

• Positive Control 3 :

  Mouse kidney

• Positive Control 4 :

  Mouse lung

• Positive Control 5 :

  Mouse spleen

• Positive Control 6 :

  Rat liver

• NCBI Official Name :

  C-mer proto-oncogene tyrosine kinase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  MERTK, c-mer proto-oncogene tyrosine kinase , MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid