RIP3 Antibody

• Background:

  The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

• NCBI Gene ID:

  11035

• Swiss Prot:

  Q9Y572

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RIP3 (NP_006862.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 45-70kDa

• Fragment:

  IgG

• Symbol:

  RIPK3

• Positive Control 2:

  Mouse spleen

• Positive Control 3:

  Mouse lung

• Positive Control 4:

  Rat lung

• NCBI Official Name:

  Receptor-interacting serine-threonine kinase 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RIPK3, RIP3, RIP3 beta, RIP3 gamma

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid