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RIPK3 Antibody

CAT: 0223-57-813Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-813Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
NCBI Gene ID
11035
Swiss Prot
Q9Y572
Accession Number
Q9Y572
Host
Rabbit
Reactivity
Human
Immunogen
This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human RIPK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
RIPK3
NCBI Official Name
Receptor-interacting serine/threonine-protein kinase 3
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Vandenabeele, P., et al. Sci Signal (115), RE4 (2010) :
Background Reference 03
Cho, Y.S., et al. Cell 137 (6) :1112-1123 (2009)
Background Reference 04
He, S., et al. Cell 137 (6) :1100-1111 (2009)
Other Product Names
Receptor-interacting serine/threonine-protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3
Tested Applications
WB, IHC-P
Protein ID
205371831
Physical Properties
Liquid

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