AMPH Antibody

• Background:

  This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

• NCBI Gene ID:

  273

• Swiss Prot:

  P49418

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 340-620 of human AMPH (NP_001626.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  PC-12

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 120kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  AMPH

• Positive Control 2:

  293T

• Positive Control 3:

  Mouse brain

• NCBI Official Name:

  Amphiphysin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AMPH, amphiphysin (Stiff-Man syndrome with breast cancer 128 kDa autoantigen), HGNC:471, AMPH1, amphiphysin, amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen)

• Tested Applications:

  WB

• Physical Properties:

  Liquid