ATL1 Antibody

• Background:

  The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

• NCBI Gene ID:

  51062

• Swiss Prot:

  Q8WXF7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATL1 (NP_056999.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 64kDa

• Fragment:

  IgG

• Symbol:

  ATL1

• Positive Control 2:

  LOVO

• Positive Control 3:

  H460

• Positive Control 4:

  293T

• Positive Control 5:

  U-87MG

• Positive Control 6:

  U-251MG

• NCBI Official Name:

  Atlastin-1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Atlastin-1, 365-, Brain-specific GTP-binding protein, GTP-binding protein 3, GBP-3, hGBP3, Guanine nucleotide-binding protein 3, Spastic paraplegia 3 protein A, ATL1, GBP3, SPG3A

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid