RACGAP1 Antibody

• Background:

  This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.

• NCBI Gene ID:

  29127

• Swiss Prot:

  Q9H0H5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 353-632 of human RACGAP1 (NP_001119576.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 82kDa

• Fragment:

  IgG

• Symbol:

  RACGAP1

• Positive Control 2:

  K-562

• Positive Control 3:

  Jurkat

• NCBI Official Name:

  Rac GTPase activating protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RACGAP1, CYK4, ID-GAP, HsCYK-4, MgcRacGAP

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid