NHEJ1 Antibody

• Background:

  Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

• NCBI Gene ID:

  79840

• Swiss Prot:

  Q9H9Q4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human NHEJ1 (NP_079058.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Hela

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 38kDa

• Fragment:

  IgG

• Symbol:

  NHEJ1

• Positive Control 2:

  Jurkat

• NCBI Official Name:

  Nonhomologous end-joining factor 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NHEJ1, nonhomologous end-joining factor 1, FLJ12610, XLF, Cernunnos, XRCC4-like factor

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid