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NHEJ1 Antibody

CAT: 0223-57-772Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-772Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
NCBI Gene ID
79840
Swiss Prot
Q9H9Q4
Accession Number
Q9H9Q4
Host
Rabbit
Reactivity
Human
Immunogen
This NHEJ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-296 amino acids from the C-terminal region of human NHEJ1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NHEJ1
NCBI Official Name
Non-homologous end-joining factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Malivert, L., et al. J. Biol. Chem. 285 (34) :26475-26483 (2010)
Background Reference 02
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 03
Okada, Y., et al. Hum. Mol. Genet. 19 (11) :2303-2312 (2010)
Background Reference 04
Andres, S.N., et al. Mol. Cell 28 (6) :1093-1101 (2007)
Other Product Names
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor, NHEJ1, XLF
Tested Applications
WB
Protein ID
74734059
Physical Properties
Liquid

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