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UCP2 Antibody

CAT: 0223-19-299Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-19-299Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.
NCBI Gene ID
7351
Swiss Prot
P55851
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human UCP2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity
Purification
Affinity purification
Positive Control
Mouse spleen
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Symbol
UCP2
NCBI Official Name
Uncoupling protein 2 (mitochondrial, proton carrier)
NCBI Organism
Homo sapiens
Other Product Names
UCP2, uncoupling protein 2 (mitochondrial, proton carrier), SLC25A8, UCPH, uncoupling protein 2, uncoupling protein-2
Tested Applications
WB, IHC
Physical Properties
Liquid

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