DYNLT1 Antibody

• Background :

  This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID :

  6993

• Swiss Prot :

  P63172

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1 (NP_006510.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 13kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:200 - 1:2000

• Symbol :

  DYNLT1

• Positive Control 2 :

  MCF7

• Positive Control 3 :

  Mouse thymus

• Positive Control 4 :

  Mouse heart

• NCBI Official Name :

  Dynein light chain Tctex-type 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1, T-complex testis-specific protein 1 homolog, t-complex-associated-testis-expressed 1-like 1

• Tested Applications :

  WB

• Physical Properties :

  Liquid