DYNLRB1 Antibody

• Background:

  This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.

• NCBI Gene ID:

  83658

• Swiss Prot:

  Q9NP97

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 20kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  DYNLRB1

• Positive Control 2:

  Mouse brain

• NCBI Official Name:

  Dynein light chain roadblock-type 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BITH, BLP, DNCL2A, DNLC2A, ROBLD1, dynein light chain roadblock-type 1, ROBL/LC7-like 1, bithoraxoid-like protein, dynein, cytoplasmic, light polypeptide 2A, dynein-associated protein Km23, roadblock domain-containing protein 1

• Tested Applications:

  WB

• Physical Properties:

  Liquid