PMM2 Antibody

• Background:

  The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

• NCBI Gene ID:

  5373

• Swiss Prot:

  O15305

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PMM2 (NP_000294.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 28kDa

• Fragment:

  IgG

• Symbol:

  PMM2

• Positive Control 2:

  A-549

• Positive Control 3:

  HeLa

• Positive Control 4:

  293T

• Positive Control 5:

  NIH/3T3

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Phosphomannomutase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Phosphomannomutase 2, PMM 2, PMM2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid