MAPRE1 Antibody

• Background:

  The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.

• NCBI Gene ID:

  22919

• Swiss Prot:

  Q15691

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 134-268 of human MAPRE1 (NP_036457.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  B-cell

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 34kDa

• Fragment:

  IgG

• Symbol:

  MAPRE1

• Positive Control 2:

  U-87MG

• Positive Control 3:

  LO2

• Positive Control 4:

  HT-29

• Positive Control 5:

  NIH/3T3

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  Microtubule-associated protein RP/EB family member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1, EB1, MAPRE1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid