LTA4H Antibody

• Background:

  The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD) . Several transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  4048

• Swiss Prot:

  P09960

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Innate Immunity

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 69kDa

• Fragment:

  IgG

• Symbol:

  LTA4H

• Positive Control 2:

  HepG2

• Positive Control 3:

  PC-3

• Positive Control 4:

  SW620

• Positive Control 5:

  BT-474

• Positive Control 6:

  Ramos

• NCBI Official Name:

  Leukotriene A4 hydrolase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  LTA4H, LTA4

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid