PMS1 Antibody

• Background:

  This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

• NCBI Gene ID:

  5378

• Swiss Prot:

  P54277

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PMS1

• Positive Control 2:

  MCF7

• Positive Control 3:

  HT-1080

• NCBI Official Name:

  PMS1 postmeiotic segregation increased 1 (S. cerevisiae)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PMS1, PMS1 postmeiotic segregation increased 1 (S. cerevisiae), PMSL1, hPMS1, HNPCC3, postmeiotic segregation 1, human homolog of yeast mutL, MLH1

• Tested Applications:

  WB

• Physical Properties:

  Liquid