EPPIN Antibody

• Background:

  This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  57119

• Swiss Prot:

  O95925

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of human EPPIN (NP_065131.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Mouse testis

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 25kDa

• Fragment:

  IgG

• Symbol:

  EPPIN

• NCBI Official Name:

  Epididymal peptidase inhibitor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CT71, CT72, SPINLW1, WAP7, WFDC7, dJ461P17.2, eppin, WAP four-disulfide core domain protein 7, cancer/testis antigen 71, cancer/testis antigen 72, epididymal protease inhibitor, epididymis secretory sperm binding protein, protease inhibitor WAP7, serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid