Lipoamide

CAT: 0804-HY-B1142-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1142-01Size:100 mg
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Description
Lipoamide ((±) -α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway[1][2].
CAS Number
[940-69-2]
Product Name Alternative
(±) -α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
UNSPSC
12352005
Hazard Statement
H302
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Lipoamide.html
Purity
99.58
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N)CCCCC1SSCC1
Molecular Formula
C8H15NOS2
Molecular Weight
205.34
Precautions
H302
References & Citations
[1]E S Arnér, et al. Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. Biochem Biophys Res Commun. 1996 Aug 5;225 (1) :268-74.|[2]Hou Y, et al. Lipoamide Ameliorates Oxidative Stress via Induction of Nrf2/ARE Signaling Pathway in PC12 Cells. J Agric Food Chem. 2019 Jul 24;67 (29) :8227-8234.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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