KU70 Antibody

• Background:

  The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

• NCBI Gene ID:

  2547

• Swiss Prot:

  P12956

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 408-609 of human KU70 (NP_001460.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Raji

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 68kDa

• Fragment:

  IgG

• Symbol:

  XRCC6

• Positive Control 2:

  SKOV3

• Positive Control 3:

  Rat liver

• NCBI Official Name:

  X-ray repair complementing defective repair in Chinese hamster cells 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  G22P1, ML8, KU70, TLAA, CTC75, CTCBF, G22P1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid