DLC1 Antibody

• Background:

  This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

• NCBI Gene ID:

  10395

• Swiss Prot:

  Q96QB1

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse lung

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 171kDa

• Fragment:

  IgG

• Symbol:

  DLC1

• NCBI Official Name:

  Deleted in liver cancer 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DLC1, ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid