HSD3B2 Antibody

• Background:

  The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta (5) -ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

• NCBI Gene ID:

  3284

• Swiss Prot:

  P26439

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 47kDa

• Fragment:

  IgG

• Symbol:

  HSD3B2

• Positive Control 2:

  U-937

• Positive Control 3:

  COS1

• Positive Control 4:

  COS-2

• Positive Control 5:

  Mouse brain

• NCBI Official Name:

  Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HSD3B2, HSDB, HSDB3, HSD3B, SDR11E2

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid