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MRPL43 Antibody

CAT: 0223-18-102Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-18-102Size:100 µL
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]
NCBI Gene ID
84545
Swiss Prot
Q8N983
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_789762.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MRPL43
Positive Control 2
PC-3
Positive Control 3
293T
NCBI Official Name
Mitochondrial ribosomal protein L43
NCBI Organism
Homo sapiens
Other Product Names
L43mt, MRP-L43, bMRP36a, 39S ribosomal protein L43, mitochondrial, mitochondrial large ribosomal subunit protein mL43, mitochondrial ribosomal protein bMRP36a
Tested Applications
WB
Physical Properties
Liquid

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