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MRPL23 Antibody

CAT: 0223-16-597Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-597Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
NCBI Gene ID
6150
Swiss Prot
Q16540
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human MRPL23 (NP_066957.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 15kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MRPL23
Positive Control 2
U-251MG
Positive Control 3
A-549
Positive Control 4
Mouse liver
Positive Control 5
Mouse lung
Positive Control 6
Mouse brain
NCBI Official Name
Mitochondrial ribosomal protein L23
NCBI Organism
Homo sapiens
Other Product Names
L23MRP, RPL23, RPL23L, 39S ribosomal protein L23, mitochondrial, L23 mitochondrial-related protein, L23mt, MRP-L23, mitochondrial large ribosomal subunit protein uL23m, ribosomal protein related to L23 (mitochondrial)
Tested Applications
WB
Physical Properties
Liquid

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