FLRT2 Antibody

• Background :

  This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• NCBI Gene ID :

  23768

• Swiss Prot :

  O43155

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  A synthetic peptide of Human FLRT2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Growth Factors, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Mouse brain

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 80kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  FLRT2

• NCBI Official Name :

  Fibronectin leucine rich transmembrane protein 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Leucine-rich repeat transmembrane protein FLRT2, fibronectin-like domain-containing leucine-rich transmembrane protein 2

• Tested Applications :

  WB

• Physical Properties :

  Liquid