FLRT1 Recombinant Protein

CAT: 0223-91-321Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-321Size:0.05 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1) is a member of the Fibronectin Leucine Rich Transmembrane protein (FLRT) family. There are three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell association. FLRT1 is expressed at brain compartmental boundaries. FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK) .
CAS Number
9000-83-3
NCBI Gene ID
23769
Swiss Prot
Q9NZU1
Accession Number
Q9NZU1
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
56.52 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Fibronectin leucine rich transmembrane protein 1
NCBI Organism
Homo sapiens
Other Product Names
Leucine-Rich Repeat Transmembrane Protein FLRT1, Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 1, FLRT1
Species
Human
Physical Properties
Lyophilized

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