SCNN1B Antibody

• Background:

  Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

• NCBI Gene ID:

  6338

• Swiss Prot:

  P51168

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Monkey

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 406-640 of human SCNN1B (NP_000327.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 75kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  SCNN1B

• Positive Control 2:

  LO2

• Positive Control 3:

  Mouse lung

• NCBI Official Name:

  Sodium channel, non-voltage-gated 1, beta subunit

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta

• Tested Applications:

  WB

• Physical Properties:

  Liquid