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SCNN1D Antibody

CAT: 0223-59-370Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-370Size:400 µL
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Background
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
NCBI Gene ID
6339
Swiss Prot
P51172
Accession Number
P51172
Host
Rabbit
Reactivity
Human
Immunogen
This SCNN1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human SCNN1D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SCNN1D
NCBI Official Name
Amiloride-sensitive sodium channel subunit delta
NCBI Organism
Homo sapiens
Background Reference 01
Wesch, D., et al. Am. J. Physiol., Cell Physiol. 299 (4), C779-C790 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Bangel-Ruland, N., et al. Am. J. Respir. Cell Mol. Biol. 42 (4) :498-505 (2010)
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na (+) channel subunit delta, Delta-ENaC, ENaCD, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D, DNACH
Tested Applications
WB
Protein ID
116242784
Physical Properties
Liquid

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