SP140 Antibody

• Background:

  This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]

• NCBI Gene ID:

  11262

• Swiss Prot:

  Q13342

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SP140 (NP_001265380) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Transcription

• Purification:

  Affinity purification

• Positive Control:

  Mouse spleen

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 98kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  SP140

• Positive Control 2:

  Mouse thymus

• Positive Control 3:

  Rat thymus

• NCBI Official Name:

  SP140 nuclear body protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SP140, LYSP100, LYSP100-A, LYSP100-B

• Tested Applications:

  WB

• Physical Properties:

  Liquid