PAK3 Antibody

• Background:

  The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47) . Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  5063

• Swiss Prot:

  O75914

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (NP_001121638.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Fragment:

  IgG

• Symbol:

  PAK3

• NCBI Official Name:

  P21 protein (Cdc42/Rac) -activated kinase 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PAK3, Beta-PAK, BPAK, MRX47, HPAK3, Oligophrenin-3, PAK3beta, MRX30, OPHN3, p21-activated kinase 3, PAK-3, BetaPak

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid