PAK1 Antibody

• Background:

  This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5058

• Swiss Prot:

  Q13153

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PAK1 (NP_002567.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Fragment:

  IgG

• Symbol:

  PAK1

• NCBI Official Name:

  P21 protein (Cdc42/Rac) -activated kinase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PAK1, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), MGC130000, MGC130001, PAKalpha, p21-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid