CYP26A1 Antibody

• Background:

  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported.

• NCBI Gene ID:

  1592

• Swiss Prot:

  O43174

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CYP26A1 (NP_000774.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 55kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CYP26A1

• NCBI Official Name:

  Cytochrome P450, family 26, subfamily A, polypeptide 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CYP26A1, cytochrome P450, family 26, subfamily A, polypeptide 1, CP26, CYP26, P450RAI, P450RAI1, P450, retinoic acid-inactivating, 1, cytochrome P450, subfamily XXVIA, polypeptide 1, retinoic acid 4-hydroxylase, retinoic acid-metabolizing cytochrome

• Tested Applications:

  WB

• Physical Properties:

  Liquid